CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46473
Family Name Sodium channel protein type 1 subunit alpha and Sodium channel protein type 2 subunit alpha ligand AGN-PC-074CPW family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00527941 Functional Category Bioactive
Superfamily Beta-lactamase and Nuclear receptor ROR-gamma Binder Superfamily 21
Class Class 1458

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Cathepsin L1 and Cathepsin S inhibitor arylaminoethyl amide, 5... 4 5
Receptor-type tyrosine-protein kinase FLT3 ligand (3Z)-5-chlor... 1 4
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Bifunctional epoxide hydrolase 2 and RAF proto-oncogene serine... 4 10
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJY family 5 4
Beta-1 adrenergic receptor and Beta-3 adrenergic receptor liga... 2 0
Thioredoxin glutathione reductase and Microtubule-associated p... 1 2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00527939 CHEMBL64018 Bioactive AGN-PC-074CFC
CFAMM00527941 CHEMBL416848 Bioactive AGN-PC-074CPW
CFAMM00527940 CHEMBL433100 Bioactive AGN-PC-074CEV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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