CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46542
Family Name Cholesteryl ester transfer protein inhibitor [8-[(1S)-1-hydroxy-3-methylbutyl]-7-methoxy-3-methyl-6-oxobenzo[b][1,4]benzodioxepin-1-yl] propane-2-sulfonate family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00528052 Functional Category Bioactive
Superfamily Cholesteryl ester transfer protein inhibitor [8-[(1S)-1-hydroxy-3-methylbutyl]-7-methoxy-3-methyl-6-oxobenzo[b][1,4]benzodioxepin-1-yl] propane-2-sulfonate Superfamily
Class Class 4969

Cousin Family NamesSeedsMembers
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
taste receptor Ligand Cynarin Family 6 124
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Endothelin-1 receptor Ligand PD156707 Family 41 211
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Protein kinase C alpha type and Protein kinase C beta type Inh... 2 1
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 1 6
Heat shock cognate 71 kDa protein Inhibitor NSC-119913 Family 2 1
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 0
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Cholesteryl ester transfer protein inhibitor [8-[(1S)-1-hydrox... 4 10
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-2-methyl-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00528052 CHEMBL425360 Bioactive [8-[(1S)-1-hydroxy-3-methylbutyl]-7-methoxy-3-methyl-6-oxobenzo[b][1,4]benzodioxepin-1-yl] propane-2-sulfonate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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