CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46561
Family Name Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00528083 Functional Category Bioactive
Superfamily Pol polyprotein and Glucagon receptor Binder Superfamily
Class Class 281

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family 2 30
Histamine H1 receptor Ligand Tranilast Family 5 125
D(4) dopamine receptor Ligand PD-165167 Family 2 96
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Epidermal growth factor receptor and Tyrosine-protein kinase L... 1 26
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Epidermal growth factor receptor Ligand 4-acrylamido-n-(3-brom... 2 20
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-(4... 2 6
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-02INEQ... 6 6
Nuclear receptor ROR-gamma and Menin ligand CHEMBL1432265 family 1 18
Thyroid hormone receptor beta ligand SureCN8800248 family 3 10
Prostaglandin D2 receptor 2 ligand 2-[4-methoxy-3-[2-[[(1S)-1-... 5 28
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Bifunctional epoxide hydrolase 2 inhibitor Urea-based compound... 1 3
Leukotriene B4 receptor 1 ligand 4-methoxy-3-[[(E)-3-(4-phenyl... 2 10
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Neprilysin inhibitor 5-[[(2S,4S)-2-benzyl-4-carboxy-5-phenylpe... 1 0
Major prion protein and Microtubule-associated protein tau inh... 2 10
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 0
2-carboxy-5-[[(E)-3-(4-methoxyphenyl)-3-oxoprop-1-enyl]amino]p... 1 0
N-[3-[(E)-3-(dimethylamino)prop-2-enoyl]-4-hydroxyphenyl]aceta... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00528083 CHEMBL428784 Bioactive NSC211094

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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