CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Sigma non-opioid intracellular receptor 1 and Histamine H1 receptor ligand AGN-PC-04SA4M family
No. of Seeds 5 No. of Other Members 9
Family Centroid CFAMM00311831 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 and Cytochrome P450 2D6 Binder Superfamily
Class Class 32

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 23
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 18 12
Neuropeptide Y receptor type 5 ligand FR-235656 family 4 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 2
Sigma non-opioid intracellular receptor 1 ligand 3-[4-(azepan-... 8 1
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3... 2 0


External ID

Functional Category

Molecule Name

CFAMM00311829 CHEMBL108157 Bioactive AGN-PC-074VB8
CFAMM00311834 CHEMBL15601 Bioactive AGN-PC-01MNUT
CFAMM00311836 CHEMBL280063 Bioactive AGN-PC-01MNUS
CFAMM00311832 CHEMBL15456 Bioactive 6-[4-[4-[(3,4-dichlorophenyl)methyl]piperazin-1-yl]butyl]-3-methyl-1,3-benzothiazol-2-one
CFAMM00311831 CHEMBL15637 Bioactive AGN-PC-04SA4M

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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