CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46601
Family Name Eukaryotic elongation factor 2 kinase and Proto-oncogene tyrosine-protein kinase Src inhibitor TX-1918 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00528150 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 Inhibitor Tebufelone Superfamily
Class Class 121

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
Oestrogen receptor ligand Dienestrol Family 35 440
Danthron family 11 141
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Arachidonate 5-lipoxygenase Inhibitor Caffeic Acid Family 3 32
Bile acid receptor Ligand SR-45023A (apomine) Family 3 34
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 2 19
Steryl-sulfatase Inhibitor Sulfamic Acid 3-(4-hydroxy-benzoyl)... 3 2
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor propan... 3 5
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 3
2,4-diacetyl-5-hydroxy-3-(4-hydroxyphenyl)-5-methylcyclohexen-... 4 0
[(E)-3-carboxy-2-(5-methyl-2-oxidophenyl)prop-2-enyl]-(2-pheny... 3 0
Putative NP ZINC03197541 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00528150 CHEMBL437612 Bioactive TX-1918

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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