CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46676
Family Name Transcriptional activator protein LuxR inhibitor 3-(3-iodophenyl)-N-[(3S)-2-oxooxolan-3-yl]propanamide family
No. of Seeds 8 No. of Other Members 2
Family Centroid CFAMM00528377 Functional Category Bioactive
Superfamily Transcriptional activator protein TraR and Transcriptional activator protein LuxR Binder Superfamily
Class Class 2584

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Tyrosine 3-monooxygenase Inhibitor L-phenylalanine Family 19 144
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Neprilysin Inhibitor Thiorphan Family 41 68
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin B and Cathepsin K Inhibitor (s)-1-benzylcyclopentyl ... 11 5
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Cytosolic phospholipase A2 Inhibitor Methyl 2-(2-oxo-8-phenylo... 2 3
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Histone deacetylase 1 and Histone deacetylase 8 inhibitor meth... 1 3
Gamma-secretase subunit PEN-2 inhibitor SureCN5966881 family 1 9
Pol polyprotein inhibitor methyl (2S)-2-[[(2S)-2-[[(2S)-2-[5-[... 1 2


External ID

Functional Category

Molecule Name

CFAMM00528373 CHEMBL511677 Bioactive 2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-[(3S)-2-oxooxolan-3-yl]acetamide
CFAMM00528379 CHEMBL467396 Bioactive N-[(3S)-2-oxooxolan-3-yl]-3-[4-(trifluoromethyl)phenyl]propanamide
CFAMM00528372 CHEMBL468790 Bioactive 2-(4-iodophenyl)-N-[(3S)-2-oxooxolan-3-yl]acetamide
CFAMM00528377 CHEMBL450689 Bioactive 3-(3-iodophenyl)-N-[(3S)-2-oxooxolan-3-yl]propanamide
CFAMM00528376 CHEMBL513503 Bioactive N-[(3S)-2-oxooxolan-3-yl]-3-[3-(trifluoromethyl)phenyl]propanamide
CFAMM00528375 CHEMBL468624 Bioactive N-[(3S)-2-oxooxolan-3-yl]-2-[4-(trifluoromethyl)phenyl]acetamide
CFAMM00528374 CHEMBL473592 Bioactive 3-oxo-N-[(3S)-2-oxooxolan-3-yl]-4-phenylbutanamide
CFAMM00528380 CHEMBL467397 Bioactive 3-(4-iodophenyl)-N-[(3S)-2-oxooxolan-3-yl]propanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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