CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46740
Family Name Calpain-1 catalytic subunit inhibitor (3S)-3-[[4-[2-(methoxymethoxy)phenyl]-4-oxobutanoyl]amino]-2-oxo-4-phenylbutanamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00528553 Functional Category Bioactive with Natural Product
Superfamily Retinal dehydrogenase 1 and Thioredoxin glutathione reductase Binder Superfamily 3
Class Class 5538

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoy... 1 3
Putative NP ZINC08790414 Family 23 0
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
Putative NP ZINC08790868 Family 10 0
Putative NP ZINC02124510 Family 1 0
NP 2-((5-hydroxy-2,2-dimethyl-4-oxochroman-7-yl)oxy)-n-(3-meth... 18 0
Putative NP ZINC04085259 Family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00528551 CHEMBL459288 Bioactive (3S)-3-[[4-[4-methoxy-2-(methoxymethoxy)phenyl]-4-oxobutanoyl]amino]-2-oxo-4-phenylbutanamide
CFAMM00528553 CHEMBL458859 Bioactive (3S)-3-[[4-[2-(methoxymethoxy)phenyl]-4-oxobutanoyl]amino]-2-oxo-4-phenylbutanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42754 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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