CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4675
Family Name Chymotrypsin-like elastase family member 1 and Neutrophil elastase inhibitor (2S)-1-[(2S)-2-[[(2S)-2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]propanoyl]amino]propanoyl]-N-[(3S)-1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl]pyrrolidine-2-carboxamide family
No. of Seeds 1 No. of Other Members 12
Family Centroid CFAMM00358127 Functional Category Bioactive
Superfamily Prothrombin and Cationic trypsin Binder Superfamily 6
Class Class 3699

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Argatroban Family 5 41
C-C chemokine receptor type 8 Ligand N-(4-phenylsulfamoyl-naph... 4 62
Interstitial collagenase and Neutrophil collagenase inhibitor ... 3 9
Neutrophil elastase inhibitor SureCN7448165 family 2 4
Cellular tumor antigen p53 inhibitor CHEMBL1554992 family 1 0
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
5-hydroxytryptamine receptor 1A ligand AGN-PC-080K14 family 3 3
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
C-C chemokine receptor type 8 ligand 3-pyrrolidin-1-ylpropyl 4... 2 0
Prothrombin and Proteinase-activated receptor 1 ligand (2S)-N-... 2 4
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-nitrophen... 1 1
Prothrombin inhibitor (2S)-3-[4-[amino(hydrazinyl)methyl]pheny... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00358127 CHEMBL339870 Bioactive (2S)-1-[(2S)-2-[[(2S)-2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]propanoyl]amino]propanoyl]-N-[(3S)-1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl]pyrrolidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27509 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543