CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46772
Family Name Acetylcholinesterase and Butyrylcholinesterase inhibitor (2Z)-5,6-dimethoxy-2-[[4-(pyrrolidin-1-ylmethyl)phenyl]methylidene]-1-benzofuran-3-one family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00528604 Functional Category Bioactive with Natural Product
Superfamily Muscarinic acetylcholine receptor Ligand Mebeverine Superfamily
Class Class 333

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Rotenone family 16 107
Heat shock protein 90, putative Inhibitor KW-2478 Family 1 14
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
D(2) dopamine receptor ligand (E)-2,3-dihydroxybut-2-enedioic ... 6 10
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 2 20
Cholesteryl ester transfer protein inhibitor [8-[(1S)-1-hydrox... 4 10
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00528604 CHEMBL462837 Bioactive (2Z)-5,6-dimethoxy-2-[[4-(pyrrolidin-1-ylmethyl)phenyl]methylidene]-1-benzofuran-3-one
CFAMM00528609 CHEMBL515241 Bioactive AGN-PC-04XQBN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26375 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543