CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Cannabinoid receptor 2 ligand 8-butoxy-N-(2-fluoro-2-phenylethyl)-7-methoxy-2-oxo-1H-quinoline-3-carboxamide family
No. of Seeds 12 No. of Other Members 7
Family Centroid CFAMM00311877 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-aminobutyric acid receptor subunit beta-2 Ligand 3-demethoxy-3-l-fucopyranosylaminothiocolchicine Superfamily
Class Class 2515

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor 5... 4 24
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Potassium ... 1 15
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor 5... 4 1
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Amine oxidase [flavin-containing] A and Mitogen-activated prot... 1 71
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Cannabinoid receptor 2 ligand 8-butoxy-N-[2-(4-fluorophenyl)et... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[2-... 3 0
Cannabinoid receptor 2 ligand 8-butoxy-7-methoxy-2-oxo-1H-quin... 1 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0


External ID

Functional Category

Molecule Name

CFAMM00311893 CHEMBL203924 Bioactive N-[2-(4-chlorophenyl)ethyl]-7-methoxy-2-oxo-8-pentoxy-1H-quinoline-3-carboxamide
CFAMM00311904 CHEMBL2096743 Bioactive N-[2-(4-aminophenyl)ethyl]-8-butoxy-7-methoxy-2-oxo-1H-quinoline-3-carboxamide
CFAMM00311878 CHEMBL1822930 Bioactive 8-butoxy-N-[2-(4-fluorophenyl)ethyl]-7-methoxy-2-oxo-1H-quinoline-3-carboxamide
CFAMM00311877 CHEMBL1822932 Bioactive 8-butoxy-N-(2-fluoro-2-phenylethyl)-7-methoxy-2-oxo-1H-quinoline-3-carboxamide
CFAMM00311887 CHEMBL1822929 Bioactive N-[2-(4-fluorophenyl)ethyl]-7,8-dimethoxy-2-oxo-1H-quinoline-3-carboxamide
CFAMM00311886 CHEMBL1822928 Bioactive 8-butoxy-N-[(4-fluorophenyl)methyl]-7-methoxy-2-oxo-1H-quinoline-3-carboxamide
CFAMM00311897 CHEMBL1822940 Bioactive N-[2-(4-fluorophenyl)ethyl]-7-methoxy-2-oxo-8-propoxy-1H-quinoline-3-carboxamide
CFAMM00311884 CHEMBL178372 Bioactive JTE 907
CFAMM00311896 CHEMBL1822943 Bioactive 7-methoxy-1-methyl-N-(2-morpholin-4-ylethyl)-2-oxo-8-pentoxyquinoline-3-carboxamide
CFAMM00311883 CHEMBL600647 Bioactive N-[2-(4-fluorophenyl)ethyl]-7-methoxy-2-oxo-8-pentoxy-1H-quinoline-3-carboxamide
CFAMM00311894 CHEMBL1081610 Bioactive 8-butoxy-N-cyclohexyl-7-methoxy-2-oxo-1H-quinoline-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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