CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46843
Family Name Heme oxygenase 1 inhibitor 1-[[(2R,4R)-2-[2-(4-chlorophenyl)ethyl]-4-(phenoxymethyl)-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00528805 Functional Category Bioactive
Superfamily Heme oxygenase 1 and Heme oxygenase 2 Binder Superfamily
Class Class 123

Cousin Family NamesSeedsMembers
14-alpha sterol demethylase inhibitor imidazole derivative Mi... 6 59
14-alpha sterol demethylase Inhibitor Terconazole Family 4 46
14-alpha sterol demethylase inhibitor imidazole derivative Ti... 2 2
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Aromatase Inhibitor NSC-289311 Family 2 1
Heme oxygenase 1 Inhibitor Azalanstat Family 1 17
Aromatase inhibitor AGN-PC-075MOK family 1 4
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 4 6
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 0
Thromboxane-A synthase inhibitor ethyl 4-[[2-[(4-ethoxycarbony... 1 5
Heme oxygenase 1 and Heme oxygenase 2 inhibitor imidazole-diox... 2 15


External ID

Functional Category

Molecule Name

CFAMM00528799 CHEMBL472795 Bioactive 1-[[(2R,4R)-2-[2-(4-chlorophenyl)ethyl]-4-[(4-fluorophenoxy)methyl]-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride
CFAMM00528797 CHEMBL474379 Bioactive 4-[[(2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]benzonitrile;hydrochloride
CFAMM00528805 CHEMBL472792 Bioactive 1-[[(2R,4R)-2-[2-(4-chlorophenyl)ethyl]-4-(phenoxymethyl)-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride
CFAMM00528796 CHEMBL474359 Bioactive SureCN409421

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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