CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46966
Family Name Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ligand 2-(6-phenyl-2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00529004 Functional Category Bioactive
Superfamily Adenosine receptor A2a and Alpha-2 adrenergic receptor Binder Superfamily
Class Class 1080

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Adenosine receptor A2a Ligand Dexefaroxan Family 11 46
Alpha-2 adrenergic receptor Ligand Idazoxan Family 6 26


External ID

Functional Category

Molecule Name

CFAMM00529007 CHEMBL492647 Bioactive 2-(2-methoxy-5-phenyl-3H-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
CFAMM00529006 CHEMBL492648 Bioactive 2-(3-methoxy-5-phenyl-2H-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole
CFAMM00529005 CHEMBL492445 Bioactive 2-(6-phenyl-2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole
CFAMM00529004 CHEMBL492444 Bioactive 2-(6-phenyl-2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



48680 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543