CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM47107
Family Name 72 kDa type IV collagenase and Aminopeptidase N inhibitor methyl (2S,4S)-1-acetyl-4-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]pyrrolidine-2-carboxylate family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00529288 Functional Category Bioactive with Natural Product
Superfamily Dopamine receptor Ligand Docarpamine Superfamily
Class Class 725

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Zucapsacin family 7 177
Endothelin-1 receptor Ligand Atrasentan Family 127 336
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
3-hydroxyacyl-CoA dehydrogenase type-2 and Retinal dehydrogena... 1 15
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor 2-... 4 2
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5
Protease inhibitor (2S)-N-[4-(1,3-benzodioxol-5-ylmethylamino)... 1 2
Calpain-1 catalytic subunit inhibitor (2E)-2-[(3,4-dihydroxyph... 4 0
Amino Acids and Derivatives Metabolite Caffeoyl aspartic acid ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00529288 CHEMBL515766 Bioactive methyl (2S,4S)-1-acetyl-4-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]pyrrolidine-2-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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