CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM47257
Family Name Thyroid hormone receptor beta ligand 3-(4-acetylpiperazin-1-yl)-1-(2,6-dichloro-4-hexoxyphenyl)propan-1-one family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00529572 Functional Category Bioactive
Superfamily Thyroid hormone receptor beta ligand 3-(4-acetylpiperazin-1-yl)-1-(2,6-dichloro-4-hexoxyphenyl)propan-1-one Superfamily
Class Class 3413

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Histamine H3 receptor Ligand A-349821 Family 49 228
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Histamine H3 receptor ligand 2-(3,3-difluoropyrrolidin-1-yl)-1... 2 0
Lanosterol synthase inhibitor AC1L9UWE family 1 0
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 5 0


External ID

Functional Category

Molecule Name

CFAMM00529573 CHEMBL550758 Bioactive 1-(2,6-dichloro-4-hexoxyphenyl)-3-(dimethylamino)propan-1-one
CFAMM00529572 CHEMBL551965 Bioactive 3-(4-acetylpiperazin-1-yl)-1-(2,6-dichloro-4-hexoxyphenyl)propan-1-one
CFAMM00529575 CHEMBL563871 Bioactive 1-(2,6-dichloro-4-hexoxyphenyl)-3-(4-ethylsulfonylpiperazin-1-yl)propan-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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