CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4728
Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor (2R)-2-[(3S)-3-[4-[(3,5-dimethoxyphenyl)methoxy]phenyl]-3-methyl-2-oxopyrrolidin-1-yl]-N-hydroxypropanamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00358450 Functional Category Bioactive
Superfamily Amine oxidase [flavin-containing] B and Cathepsin B Binder Superfamily
Class Class 65

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Disintegrin and metalloproteinase domain-containing protein 17... 3 2
Pol polyprotein inhibitor MDL 74538 family 11 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Follicle-stimulating hormone receptor ligand SureCN6140614 family 2 8
Cathepsin S and Cathepsin L1 inhibitor benzyl N-[(2S)-1-oxo-1-... 2 2
Stromelysin-1 and Interstitial collagenase inhibitor (2R)-2-[4... 4 1
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00358451 CHEMBL144320 Bioactive (2R)-2-[(3S)-3-[4-[[3,5-bis(trifluoromethyl)phenyl]methoxy]phenyl]-3-methyl-2-oxopyrrolidin-1-yl]-N-hydroxypropanamide
CFAMM00358450 CHEMBL143451 Bioactive (2R)-2-[(3S)-3-[4-[(3,5-dimethoxyphenyl)methoxy]phenyl]-3-methyl-2-oxopyrrolidin-1-yl]-N-hydroxypropanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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