CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM47459
Family Name Protoporphyrinogen oxidase inhibitor 3-[2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-4-fluorophenyl]-1,1-di(propan-2-yl)urea family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00529915 Functional Category Bioactive
Superfamily Protoporphyrinogen oxidase Binder Superfamily
Class Class 5273

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3


External ID

Functional Category

Molecule Name

CFAMM00529915 CHEMBL577789 Bioactive 3-[2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-4-fluorophenyl]-1,1-di(propan-2-yl)urea
CFAMM00529914 CHEMBL576572 Bioactive 3-[2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)phenyl]-1,1-dipropylurea
CFAMM00529913 CHEMBL575002 Bioactive 1-[2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-4-fluorophenyl]-3-methylurea
CFAMM00529916 CHEMBL575006 Bioactive 3-chloro-N-[2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)-4-fluorophenyl]-2,2-dimethylpropanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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