CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM47536
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor 6-[[3-(4-hydroxypiperidine-1-carbonyl)phenyl]methoxy]-4-methyl-1H-quinolin-2-one family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00530141 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor and Beta-3 adrenergic receptor Binder Superfamily 2
Class Class 4220

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand quinolone derivative Carteolol... 1 38
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Liver carboxylesterase 1 Inhibitor 5-(trifluoromethoxy)-1h-ind... 3 12
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(2) dopamine receptor Ligand Epidepride Family 31 66
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 13 20
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 6 3
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 2 1
Histamine H3 receptor and Potassium voltage-gated channel subf... 28 30
Beta-1 adrenergic receptor and Beta-3 adrenergic receptor liga... 2 0
Sodium channel protein type 1 subunit alpha and Sodium channel... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00530141 CHEMBL592241 Bioactive 6-[[3-(4-hydroxypiperidine-1-carbonyl)phenyl]methoxy]-4-methyl-1H-quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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