CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM47651
Family Name Chymase and Chymotrypsinogen A inhibitor N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-3-(2,3-dimethoxyphenyl)propanamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00530335 Functional Category Bioactive
Superfamily Chymase and Chymotrypsinogen A Binder Superfamily
Class Class 333

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Zucapsacin family 7 177
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Substance-P receptor Ligand DA-5018 Family 14 73
D(3) dopamine receptor Ligand U-99194A Family 7 33
Ivabradine family 1 11
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Cannabinoid receptor 1 Ligand N-(3,5-dimethoxyphenethyl)oleami... 5 49
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Transient receptor potential cation channel subfamily V member... 3 18
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Follicle-stimulating hormone receptor ligand SureCN6140614 family 2 8
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Cathepsin K inhibitor (2S)-2-[[2-(3,4-dimethoxyphenyl)acetyl]a... 1 1
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 10
Sodium-dependent dopamine transporter inhibitor methyl (2R)-2-... 4 3
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor 2-(3-chl... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00530335 CHEMBL61059 Bioactive N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-3-(2,3-dimethoxyphenyl)propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26406 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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