CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM47682
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7493806 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00530379 Functional Category Bioactive
Superfamily Peptide deformylase, mitochondrial Inhibitor Trimetrexate Superfamily
Class Class 377

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 6 9
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 3
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
Transient receptor potential cation channel subfamily V member... 2 4
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 1 0
Epidermal growth factor receptor ligand 4-Anilinoquinazoline d... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00530378 CHEMBL68072 Bioactive SureCN7504986
CFAMM00530379 CHEMBL63637 Bioactive SureCN7493806

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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