CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4785
Family Name Squalene synthase inhibitor (2R)-2-[2-[[(2S,3S)-4-(3,4-dichlorophenyl)-3-(3-fluoro-4-phenylphenyl)butan-2-yl]amino]-2-oxoethyl]butanedioic acid family
No. of Seeds 6 No. of Other Members 9
Family Centroid CFAMM00358907 Functional Category Bioactive
Superfamily Squalene synthase inhibitor (2R)-2-[2-[[(2S,3S)-4-(3,4-dichlorophenyl)-3-(3-fluoro-4-phenylphenyl)butan-2-yl]amino]-2-oxoethyl]butanedioic acid Superfamily
Class Class 4139

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2S,4R)... 5 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00358908 CHEMBL356514 Bioactive SureCN8623726
CFAMM00358907 CHEMBL2115091 Bioactive (2R)-2-[2-[[(2S,3S)-4-(3,4-dichlorophenyl)-3-(3-fluoro-4-phenylphenyl)butan-2-yl]amino]-2-oxoethyl]butanedioic acid
CFAMM00358913 CHEMBL61935 Bioactive (2S)-2-[2-[[(2S,3S)-4-(3,4-dichlorophenyl)-3-(4-phenylphenyl)butan-2-yl]amino]-2-oxoethyl]butanedioic acid
CFAMM00358906 CHEMBL59729 Bioactive (2S)-2-[2-[[(2S,3S)-4-(4-chlorophenyl)-3-(4-phenylphenyl)butan-2-yl]amino]-2-oxoethyl]butanedioic acid
CFAMM00358918 CHEMBL143820 Bioactive SureCN8623891
CFAMM00358911 CHEMBL61985 Bioactive (2S)-2-[2-[[(2S,3S)-4-(3,4-dichlorophenyl)-3-(3-fluoro-4-phenylphenyl)butan-2-yl]amino]-2-oxoethyl]butanedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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