CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM47906
Family Name Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibitor 2-(2-bromophenyl)-5,7-dihydroxy-8-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)chromen-4-one family
No. of Seeds 1 No. of Other Members 11
Family Centroid CFAMM00530787 Functional Category Bioactive with Natural Product
Superfamily Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibitor 2-(2-bromophenyl)-5,7-dihydroxy-8-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)chromen-4-one Superfamily
Class Class 544

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
C-C chemokine receptor type 1 and Chemokine (C-C motif) recept... 1 16
Squalene--hopene cyclase and Lanosterol synthase inhibitor R17... 1 22
Breast cancer type 1 susceptibility protein and Huntingtin inh... 1 7
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
1-benzofuran-3-one NP ZINC09486173 Family 33 0
NP Agn-pc-054n5h Family 5 0
Putative NP ZINC20357755 Family 11 0
2-(trifluoromethyl)chromen-4-one NP ZINC02418160 Family 7 0
6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one NP ZINC2... 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00530787 CHEMBL8958 Bioactive 2-(2-bromophenyl)-5,7-dihydroxy-8-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)chromen-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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