CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4791
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC-075QCD family
No. of Seeds 2 No. of Other Members 16
Family Centroid CFAMM00358958 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 4 Binder Superfamily 17
Class Class 3582

Cousin Family NamesSeedsMembers
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Prothrombin inhibitor N-(2-aminoethyl)-2-[5-[[3-(benzylsulfony... 17 5
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor (2S)-2... 2 4
A disintegrin and metalloproteinase with thrombospondin motifs... 1 0
Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1-(4-methylphenyl)sul... 1 1


External ID

Functional Category

Molecule Name

CFAMM00358958 CHEMBL143891 Bioactive AGN-PC-075QCD
CFAMM00358971 CHEMBL301811 Bioactive (2S)-N-[4-[(diaminomethylideneamino)sulfamoyl]phenyl]-3-(1H-imidazol-5-yl)-2-[3-[(4-methylphenyl)sulfonylcarbamoylamino]propanoylamino]propanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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