CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4813
Family Name Reverse transcriptase/RNaseH inhibitor Dipyridodiazepinone deriv. 61 family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00359114 Functional Category Bioactive
Superfamily Smoothened homolog Inhibitor LDE225 Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Smoothened homolog Inhibitor LDE225 Family 3 76
XL-888 family 16 85
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
Reverse transcriptase/RNaseH inhibitor AC1LALKM family 2 19
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
Prelamin-A/C and Cellular tumor antigen p53 inhibitor CHEMBL16... 1 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Reverse transcriptase/RNaseH and Cytochrome P450 2C19 inhibito... 7 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
MAP kinase-activated protein kinase 2 inhibitor N-[4-(4-oxospi... 3 0
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 9 0
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor 6-[(3... 10 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Substance-P receptor ligand Netupitant family 5 2
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 4
Adenosine receptor A2a and Adenosine receptor A1 ligand N-benz... 3 12
Metabotropic glutamate receptor 1 ligand N-(cyclopropylmethyl)... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00359114 CHEMBL144035 Bioactive Dipyridodiazepinone deriv. 61

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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