CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4831
Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-[propyl(quinolin-8-ylsulfonyl)amino]butanediamide family
No. of Seeds 5 No. of Other Members 9
Family Centroid CFAMM00359275 Functional Category Bioactive
Superfamily Disintegrin and Collagenase 3 Binder Superfamily
Class Class 3305

Cousin Family NamesSeedsMembers
Rho-associated protein kinase 1 Inhibitor Rho-kinase Inhibitor... 6 39
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 1 11
Cathepsin L1 inhibitor Bio2_000267 family 9 1
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 1 0
Neuropeptide Y receptor type 5 ligand 2-[4-(benzenesulfonamido... 2 27
Disintegrin and metalloproteinase domain-containing protein 17... 4 0
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 3
Disintegrin and metalloproteinase domain-containing protein 17... 3 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 3 2
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
Rho-associated protein kinase 2 and Ribosomal protein S6 kinas... 6 1
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-N-hydr... 1 0
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 3 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00359267 CHEMBL344759 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(quinolin-6-ylsulfonylamino)butanediamide
CFAMM00359277 CHEMBL144843 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(quinolin-8-ylsulfonylamino)butanediamide
CFAMM00359265 CHEMBL342732 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-[methyl(quinolin-8-ylsulfonyl)amino]butanediamide
CFAMM00359276 CHEMBL144293 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-3-(isoquinolin-5-ylsulfonylamino)-2-(2-methylpropyl)butanediamide
CFAMM00359275 CHEMBL144144 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-[propyl(quinolin-8-ylsulfonyl)amino]butanediamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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