CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4838
Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(quinolin-8-ylmethoxy)butanediamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00359463 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Interstitial collagenase Inhibitor BB-3644 Superfamily
Class Class 821

Cousin Family NamesSeedsMembers
CP-18770 family 6 27
Lethal factor Inhibitor GM6001 Family 50 435
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Disintegrin and metalloproteinase domain-containing protein 17... 4 0
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... 3 1
Interstitial collagenase and Stromelysin-1 inhibitor CHEMBL887... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00359463 CHEMBL144188 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(quinolin-8-ylmethoxy)butanediamide
CFAMM00359464 CHEMBL148395 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(quinoxalin-5-ylmethoxy)butanediamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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