CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4839
Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor (2R,3S)-3-[(4-acetamidophenyl)sulfonylamino]-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00359465 Functional Category Bioactive
Superfamily Cathepsin B and Disintegrin Binder Superfamily
Class Class 3199

Cousin Family NamesSeedsMembers
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Neutrophil elastase inhibitor SureCN7448165 family 2 4
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 2 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
B1 bradykinin receptor ligand N-[(4S)-1-ethyl-3,3-dimethylpipe... 10 4
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12


External ID

Functional Category

Molecule Name

CFAMM00359469 CHEMBL24347 Bioactive (2S,11S,12R)-7-(4-aminophenyl)sulfonyl-11-N-hydroxy-2-N-methyl-12-(2-methylpropyl)-13-oxo-1,7-diazacyclotridecane-2,11-dicarboxamide
CFAMM00359467 CHEMBL144206 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-[(2-oxo-1,3-dihydroindol-5-yl)sulfonylamino]butanediamide
CFAMM00359466 CHEMBL343021 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-3-[(1-methyl-2-oxo-3,4-dihydroquinolin-6-yl)sulfonylamino]-2-(2-methylpropyl)butanediamide
CFAMM00359465 CHEMBL357414 Bioactive (2R,3S)-3-[(4-acetamidophenyl)sulfonylamino]-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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