CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4882
Family Name Cellular tumor antigen p53 and Microtubule-associated protein tau inhibitor CHEMBL1445391 family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00359721 Functional Category Bioactive
Superfamily Prothrombin and P2X purinoceptor 7 Binder Superfamily
Class Class 3305

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
Histone deacetylase 1 Inhibitor Resminostat Family 2 5
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
NF-kappa-B Inhibitor 2-nitro-n-(quinolin-8-yl)benzenesulfonami... 2 3
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-(2,6... 8 60
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 1 11
Cathepsin L1 inhibitor Bio2_000267 family 9 1
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 8
Thyrotropin receptor and Huntingtin ligand CHEMBL1333081 family 1 2
Disintegrin and metalloproteinase domain-containing protein 17... 5 9
Disintegrin and metalloproteinase domain-containing protein 17... 4 0
Disintegrin and metalloproteinase domain-containing protein 17... 3 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 4-[2-(... 2 6
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 3 2
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 1 3
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 5 2
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-N-hydr... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-(2,6... 3 10
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor N-(2-c... 1 4
Cannabinoid receptor 2 ligand 1-(benzenesulfonyl)-N-quinolin-3... 2 2
Neurotensin receptor type 1 ligand (2R)-4-methyl-2-[[2-[5-(qui... 1 1
Prostaglandin G/H synthase 2 inhibitor SureCN6345015 family 6 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Coagulation factor X inhibitor (E)-2-fluoro-3-[3-(N'-methylcar... 1 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor N-(2-b... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor N-(5-c... 2 0
Neuropeptide Y receptor type 5 and Neuropeptide Y receptor typ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00359723 CHEMBL422234 Bioactive AGN-PC-074HGQ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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