CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4917
Family Name Melanin-concentrating hormone receptor 1 and Melanin-concentrating hormone receptor 2 ligand AGN-PC-00BH7I family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00290254 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Melanin-concentrating hormone receptor 2 Binder Superfamily
Class Class 216

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Histamine H3 receptor Ligand A-349821 Family 49 228
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(2) dopamine receptor Ligand Epidepride Family 31 66
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
DNA-dependent protein kinase catalytic subunit and Phosphatidy... 1 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Pol polyprotein inhibitor AC1LALH8 family 2 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0
Mineralocorticoid receptor and Glucocorticoid receptor ligand ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00359973 CHEMBL602674 Bioactive SureCN4251105
CFAMM00359980 CHEMBL215661 Bioactive AGN-PC-00DNMK

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26232 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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