CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-04Y3SZ family
No. of Seeds 17 No. of Other Members 23
Family Centroid CFAMM00312271 Functional Category Bioactive
Superfamily Menin and Prelamin-A/C Binder Superfamily
Class Class 1481

Cousin Family NamesSeedsMembers
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 1 4
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
Coagulation factor X and Prothrombin inhibitor SureCN763988 fa... 31 86
Glycogen phosphorylase, liver form inhibitor 2,3-dichloro-N-[(... 2 14
Coagulation factor X inhibitor N-[5-carbamoyl-2-[[(5-chlorothi... 8 8
Coagulation factor X inhibitor 2-carboxyindole 24 family 1 0
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Glycogen phosphorylase, liver form inhibitor SureCN5630210 family 2 0
Centromere-associated protein E inhibitor 3-bromo-N-[(3,4-dich... 1 1


External ID

Functional Category

Molecule Name

CFAMM00312227 CHEMBL1085647 Bioactive AGN-PC-04Y3SF
CFAMM00312213 CHEMBL1084899 Bioactive AGN-PC-04Y3TW
CFAMM00312222 CHEMBL1086540 Bioactive AGN-PC-04Y3T1
CFAMM00312290 CHEMBL1083165 Bioactive AGN-PC-04Y3SA
CFAMM00312240 CHEMBL1085410 Bioactive AGN-PC-04Y3S5
CFAMM00312274 CHEMBL1083728 Bioactive AGN-PC-04Y3SV
CFAMM00312221 CHEMBL1083136 Bioactive SureCN13824856
CFAMM00312225 CHEMBL1083166 Bioactive AGN-PC-04Y3SB
CFAMM00312282 CHEMBL1082796 Bioactive AGN-PC-04Y3SW
CFAMM00312271 CHEMBL1086320 Bioactive AGN-PC-04Y3SZ
CFAMM00312232 CHEMBL1085412 Bioactive AGN-PC-04Y3SJ
CFAMM00312229 CHEMBL1086565 Bioactive AGN-PC-04Y3SG
CFAMM00312248 CHEMBL1085873 Bioactive AGN-PC-04Y3S4
CFAMM00312278 CHEMBL1082455 Bioactive AGN-PC-04Y3T4
CFAMM00312267 CHEMBL1086539 Bioactive AGN-PC-04Y3T0
CFAMM00312214 CHEMBL1085411 Bioactive AGN-PC-04Y3SI
CFAMM00312247 CHEMBL1084058 Bioactive AGN-PC-04Y3TR

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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