CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4950
Family Name Inosine-5'-monophosphate dehydrogenase and Nuclear receptor ROR-gamma ligand N-naphthalen-2-yl-2-[2-(1,3-thiazol-4-yl)benzimidazol-1-yl]acetamide family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00360210 Functional Category Bioactive
Superfamily Coagulation factor X and Nuclear receptor ROR-gamma Binder Superfamily
Class Class 170

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Aurora kinase A inhibitor 2-[4-[6-chloro-2-[4-(morpholin-4-ylm... 1 2
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-07ZDR2 f... 7 33
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Metabotropic glutamate receptor 1 ligand N-cyclohexyl-7-[[2-me... 2 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Cyclin-dependent kinase 5 and G1/S-specific cyclin-E1 inhibito... 1 1
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Adenosine receptor A2b and Adenosine receptor A3 ligand 3-[5-(... 4 2
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)imidazo[1,... 5 3
Glucocorticoid receptor ligand 3-[1-(3-chloro-4-fluorophenyl)i... 2 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Aurora kinase A inhibitor AGN-PC-08002R family 1 0
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 6 0
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 1 2
Acyl-CoA desaturase 1 inhibitor N-(thiophen-2-ylmethyl)-2-[4-[... 2 0


External ID

Functional Category

Molecule Name

CFAMM00360212 CHEMBL1957252 Bioactive N-naphthalen-2-yl-2-[2-(1,3-thiazol-2-yl)benzimidazol-1-yl]acetamide
CFAMM00360210 CHEMBL1450808 Bioactive N-naphthalen-2-yl-2-[2-(1,3-thiazol-4-yl)benzimidazol-1-yl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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