CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4953
Family Name Estrogen receptor beta and Estrogen receptor ligand 3-fluoro-4-[(1R,5R,8R)-5-(hydroxymethyl)-2-methyl-7-oxabicyclo[3.3.1]non-2-en-8-yl]phenol family
No. of Seeds 6 No. of Other Members 42
Family Centroid CFAMM00360304 Functional Category Bioactive with Natural Product
Superfamily Estrogen receptor and Estrogen receptor beta Binder Superfamily 6
Class Class 785

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
Salicin family 5 629
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Glucokinase Inhibitor R7201 Family 22 105
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
TS-071 family 8 36
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Arachidonate 15-lipoxygenase Inhibitor Hydrohalisulfate 1 Family 6 6
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 2 1
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Estrogen receptor beta and Estrogen receptor ligand 3-chloro-4... 2 0
Vitamin D3 receptor ligand (1R,3S,5Z)-5-[(2E)-2-[(3aS,7aR)-1-[... 1 2
Phenols and Derivatives Metabolite 2-(Ethoxymethyl)phenol Family 1 14


External ID

Functional Category

Molecule Name

CFAMM00360265 CHEMBL181245 Bioactive 2-fluoro-4-[(1R,5R,8R)-5-(hydroxymethyl)-2-methyl-7-oxabicyclo[3.3.1]non-2-en-8-yl]phenol
CFAMM00360304 CHEMBL179295 Bioactive 3-fluoro-4-[(1R,5R,8R)-5-(hydroxymethyl)-2-methyl-7-oxabicyclo[3.3.1]non-2-en-8-yl]phenol
CFAMM00360312 CHEMBL369337 Bioactive (1R,5S,8R)-8-(2-fluoro-4-hydroxyphenyl)-2,6,6-trimethyl-7-oxabicyclo[3.3.1]non-2-en-5-ol
CFAMM00360273 CHEMBL178364 Bioactive 2-fluoro-4-[(1R,5R,8S)-5-(hydroxymethyl)-1,2-dimethyl-7-oxabicyclo[3.3.1]non-2-en-8-yl]phenol
CFAMM00360286 CHEMBL181191 Bioactive (1R,5S,8R)-8-(3-fluoro-4-hydroxyphenyl)-2,6,6-trimethyl-7-oxabicyclo[3.3.1]non-2-en-5-ol
CFAMM00360291 CHEMBL360127 Bioactive (1R,5S,8R)-8-(4-hydroxyphenyl)-2,6,6-trimethyl-7-oxabicyclo[3.3.1]non-2-en-5-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



85241 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543