| Cousin Family Names | Seeds | Members |
|---|
| 5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... | 14 | 498 |
| D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... | 12 | 720 |
| 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... | 4 | 171 |
| Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... | 5 | 644 |
| 5-hydroxytryptamine receptor 1D Ligand Rizatriptan Family | 7 | 460 |
| Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family | 32 | 639 |
| D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family | 5 | 74 |
| Omega 1 Benzodiazepine receptor Ligand Zaleplon Family | 6 | 589 |
| Toll-like receptor 7 Ligand Imiquimod Family | 3 | 237 |
| Acetylcholinesterase Inhibitor Tacrine Family | 12 | 515 |
| Amiloride-sensitive sodium channel subunit alpha Ligand Triamt... | 8 | 98 |
| Histamine H1 receptor Ligand Pheniramine Family | 10 | 380 |
| Histamine H1 receptor Ligand Triprolidine Family | 19 | 316 |
| Type-1 angiotensin II receptor Ligand Forasartan Family | 3 | 253 |
| Histamine H1 receptor Ligand Mizolastine Family | 14 | 603 |
| Transient receptor potential cation channel subfamily V member... | 15 | 158 |
| Metabotropic glutamate receptor 5 Ligand ADX-48621 Family | 15 | 444 |
| C-X-C chemokine receptor type 4 Ligand AMD-070 Family | 12 | 800 |
| Transient receptor potential cation channel subfamily V member... | 16 | 295 |
| Farnesyltransferase beta subunit, putative Inhibitor BMS214662... | 11 | 65 |
| Transient receptor potential cation channel subfamily V member... | 15 | 457 |
| Vascular endothelial growth factor Inhibitor PTC299 Family | 6 | 145 |
| Transient receptor potential cation channel subfamily V member... | 6 | 66 |
| Cyclin-dependent kinase 2 Inhibitor Seliciclib Family | 29 | 292 |
| Calcitonin gene-related peptide type 1 receptor Ligand Telcage... | 25 | 124 |
| Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... | 10 | 56 |
| Fibroblast growth factor receptor 2 and Fibroblast growth fact... | 11 | 86 |
| Cyclin-dependent kinase 4 Inhibitor PD-332991 Family | 13 | 155 |
| Tyrosine-protein kinase JAK2 Inhibitor INCB18424 Family | 3 | 130 |
| Potassium voltage-gated channel subfamily KQT member 1 Ligand ... | 13 | 242 |
| Reverse transcriptase Inhibitor Dapivirine Family | 5 | 72 |
| D(1B) dopamine receptor Ligand LE-300 Family | 65 | 452 |
| 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... | 14 | 234 |
| Adenosine receptor A1 Ligand SLV320 Family | 6 | 79 |
| Protein kinase C alpha type and Protein kinase C beta type Inh... | 16 | 86 |
| Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family | 53 | 580 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 2 | 9 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 35 | 270 |
| Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... | 13 | 55 |
| Amg 423 family | 7 | 47 |
| GDC-0349 family | 44 | 77 |
| Histone deacetylase Inhibitor JNJ-26481585 Family | 2 | 5 |
| E7820 family | 9 | 56 |
| Vascular endothelial growth factor receptor 2 Ligand XL999 Family | 11 | 87 |
| 5-hydroxytryptamine receptor 2A Ligand RP-68303 Family | 7 | 44 |
| PF-4217903 family | 14 | 65 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... | 8 | 55 |
| Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family | 9 | 29 |
| Tryptase Inhibitor Babim Family | 12 | 90 |
| Nicotinic acetylcholine receptor Ligand Epibatidine Family | 36 | 19 |
| D(4) dopamine receptor Ligand L-745,870 Family | 30 | 205 |
| 5-hydroxytryptamine receptor 2B Ligand MT-500 Family | 8 | 39 |
| CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... | 2 | 7 |
| Corticotropin-releasing factor receptor 1 Ligand R121919 Family | 26 | 84 |
| Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family | 3 | 33 |
| Interleukin-1 receptor type 1 and Mitogen-activated protein ki... | 7 | 151 |
| 5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family | 14 | 21 |
| Histamine H3 receptor Ligand SCH79687 Family | 11 | 29 |
| Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... | 10 | 43 |
| Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... | 31 | 66 |
| Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... | 13 | 14 |
| D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... | 6 | 48 |
| 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... | 4 | 32 |
| Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... | 18 | 109 |
| Vascular endothelial growth factor receptor 1 and Vascular end... | 6 | 23 |
| Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... | 7 | 117 |
| Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... | 14 | 13 |
| Epidermal growth factor receptor Ligand PD-158780 Family | 98 | 89 |
| D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... | 7 | 102 |
| Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... | 3 | 18 |
| Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... | 2 | 5 |
| Glycogen synthase kinase-3 beta Inhibitor N-(6-(pyridin-4-yl)-... | 4 | 23 |
| Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... | 3 | 16 |
| Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... | 6 | 19 |
| Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... | 4 | 9 |
| Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... | 5 | 3 |
| Aromatase and Thromboxane-A synthase Inhibitor 6-(1h-imidazol-... | 3 | 8 |
| Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... | 6 | 5 |
| Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... | 19 | 165 |
| Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family | 14 | 103 |
| Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... | 7 | 12 |
| Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... | 8 | 5 |
| Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... | 17 | 29 |
| Alpha-1A adrenergic receptor Ligand A-315456 Family | 7 | 17 |
| RAC-gamma serine/threonine-protein kinase and Rho-associated p... | 16 | 46 |
| Adenosine receptor A3 and Dual specificity mitogen-activated p... | 5 | 27 |
| Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... | 3 | 6 |
| Metabotropic glutamate receptor 5 Ligand 2-m-tolyl-1,8-naphthy... | 7 | 11 |
| Adenosine receptor A3 Ligand 2-(4-nitro-1h-benzo[d]imidazol-2-... | 2 | 12 |
| DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... | 2 | 6 |
| Delta-type opioid receptor and Kappa-type opioid receptor Liga... | 5 | 45 |
| 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... | 3 | 2 |
| Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family | 112 | 67 |
| Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... | 6 | 24 |
| Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... | 28 | 47 |
| Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... | 38 | 60 |
| Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... | 3 | 9 |
| Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... | 41 | 59 |
| Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... | 8 | 11 |
| Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... | 7 | 7 |
| Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... | 5 | 13 |
| Mitogen-activated protein kinase kinase kinase 8 and Stromelys... | 6 | 53 |
| Fatty-acid amide hydrolase 1 Inhibitor JNJ-1661010 Family | 3 | 14 |
| Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... | 6 | 3 |
| Aromatase Inhibitor NSC-356781 Family | 3 | 10 |
| Macrophage migration inhibitory factor Inhibitor 4-iodo-6-phen... | 5 | 4 |
| Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family | 4 | 1 |
| Histamine H4 receptor Ligand A-943931 Family | 14 | 11 |
| RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... | 219 | 124 |
| Potassium voltage-gated channel subfamily H member 2 Ligand AZ... | 21 | 42 |
| Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family | 5 | 6 |
| Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... | 7 | 18 |
| Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... | 2 | 2 |
| Serine/threonine-protein kinase mTOR Inhibitor 4-(2-(1h-indol-... | 2 | 15 |
| Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... | 3 | 0 |
| Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... | 5 | 16 |
| Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... | 94 | 23 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... | 6 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-1 Ligand N-(9h-... | 5 | 2 |
| Sodium-dependent serotonin transporter Inhibitor 6-nitroquipaz... | 18 | 21 |
| Type-2 angiotensin II receptor Ligand L-158809 Family | 22 | 136 |
| Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... | 3 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... | 6 | 55 |
| Peptide deformylase, mitochondrial Inhibitor 7h-pyrrolo[3,2-f]... | 2 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... | 3 | 2 |
| Sodium channel protein type 1 subunit alpha and Sodium channel... | 10 | 14 |
| Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... | 6 | 10 |
| Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... | 6 | 3 |
| Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... | 14 | 22 |
| Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... | 6 | 16 |
| Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... | 42 | 7 |
| Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... | 62 | 27 |
| Choline kinase alpha Inhibitor Bisquinolinium Derivative Family | 10 | 7 |
| Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... | 25 | 10 |
| Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... | 3 | 13 |
| Prothrombin inhibitor SureCN5854779 family | 4 | 9 |
| Prothrombin inhibitor SureCN5856722 family | 3 | 16 |
| Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... | 14 | 4 |
| Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family | 6 | 13 |
| Protein kinase C theta type and Protein kinase C delta type in... | 7 | 17 |
| Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... | 2 | 3 |
| Corticotropin-releasing factor receptor 1 ligand SureCN5395386... | 6 | 5 |
| Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... | 4 | 7 |
| Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... | 4 | 0 |
| Protein kinase C theta type and Protein kinase C delta type in... | 16 | 8 |
| Histamine H3 receptor and Potassium voltage-gated channel subf... | 4 | 33 |
| Corticotropin-releasing factor receptor 1 ligand N-(cyclopropy... | 2 | 10 |
| Bombesin receptor subtype-3 ligand (2R)-1-[4-[2-[5-(2,2-dimeth... | 1 | 1 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... | 4 | 2 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 10 | 3 |
| Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... | 3 | 12 |
| Aurora kinase B inhibitor AGN-PC-07ZZ0Y family | 2 | 12 |
| Thromboxane-A synthase inhibitor AGN-PC-00N7V2 family | 3 | 6 |
| 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... | 2 | 1 |
| Leukocyte tyrosine kinase receptor and ALK tyrosine kinase rec... | 3 | 0 |
| Macrophage colony-stimulating factor 1 receptor and Cytochrome... | 13 | 3 |
| 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... | 14 | 13 |
| Platelet-activating factor receptor ligand AGN-PC-0750SP family | 4 | 0 |
| RAF proto-oncogene serine/threonine-protein kinase and Serine/... | 3 | 5 |
| 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... | 7 | 4 |
| Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... | 8 | 8 |
| Serine/threonine-protein kinase D1 inhibitor SureCN1424142 family | 13 | 8 |
| Polycystin-2 and Serine/threonine-protein kinase D1 inhibitor ... | 4 | 12 |
| Histamine H3 receptor ligand SureCN4025673 family | 4 | 2 |
| Histamine H3 receptor ligand SureCN4018269 family | 1 | 0 |
| Adenosine receptor A3 ligand 5-butyl-8-(4-methylsulfanylphenyl... | 2 | 4 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 3 | 2 |
| Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... | 7 | 10 |
| Cyclin-dependent kinase 5 and Cyclin-dependent kinase 1 inhibi... | 2 | 0 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 4 | 27 |
| DNA-dependent protein kinase catalytic subunit and Tyrosine-pr... | 2 | 10 |
| 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... | 11 | 20 |
| RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... | 2 | 4 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 2 | 3 |
| Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... | 10 | 1 |
| Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... | 3 | 11 |
| Serine/threonine-protein kinase B-raf inhibitor SureCN3495829 ... | 24 | 0 |
| Serine/threonine-protein kinase B-raf inhibitor SureCN3495787 ... | 8 | 1 |
| Survival motor neuron protein and Menin inhibitor CHEMBL132797... | 1 | 1 |
| Type-1B angiotensin II receptor ligand SureCN683399 family | 3 | 0 |
| Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... | 7 | 9 |
| Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... | 7 | 1 |
| 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... | 3 | 8 |
| Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14574... | 1 | 2 |
| Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... | 1 | 0 |
| Prelamin-A/C inhibitor CHEMBL1472945 family | 1 | 32 |
| Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... | 4 | 4 |
| Mitogen-activated protein kinase 13 and Mitogen-activated prot... | 5 | 0 |
| Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... | 4 | 2 |
| Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... | 1 | 0 |
| Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... | 5 | 0 |
| Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... | 3 | 7 |
| C-C chemokine receptor type 5 and Potassium voltage-gated chan... | 21 | 32 |
| Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... | 5 | 3 |
| Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family | 1 | 3 |
| Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... | 15 | 3 |
| Glycogen synthase kinase-3 beta and Dual specificity protein k... | 4 | 5 |
| Corticotropin-releasing factor receptor 1 ligand SureCN6301726... | 4 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... | 1 | 0 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 6 | 2 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 3 | 0 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 3 | 5 |
| Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(1H-pyr... | 2 | 8 |
| Mu-type opioid receptor and Kappa-type opioid receptor ligand ... | 3 | 0 |
| TGF-beta receptor type-1 ligand 3-(6-methylpyridin-2-yl)-N-phe... | 21 | 0 |
| Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... | 2 | 1 |
| Toll-like receptor 7 ligand 4-amino-1-[[6-[(2S)-2-(pyrrolidin-... | 4 | 0 |
| Somatostatin receptor type 5 and Somatostatin receptor type 2 ... | 6 | 3 |
| Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 4 ... | 2 | 1 |
| Sodium-dependent serotonin transporter and 5-hydroxytryptamine... | 5 | 0 |
| CGMP-dependent protein kinase inhibitor AGN-PC-075XII family | 25 | 7 |
| Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... | 7 | 0 |
| Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... | 9 | 2 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... | 2 | 0 |
| Mitogen-activated protein kinase 14 inhibitor 4-(2-chloropheny... | 4 | 0 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family | 10 | 11 |
| Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... | 5 | 4 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 4 | 2 |
| Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... | 3 | 1 |
| C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... | 3 | 2 |
| Cell division cycle 7-related protein kinase and Protein DBF4 ... | 15 | 7 |
| Mast/stem cell growth factor receptor Kit and Receptor-type ty... | 8 | 3 |
| Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... | 2 | 13 |
| Macrophage colony-stimulating factor 1 receptor and Vascular e... | 2 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... | 10 | 6 |
| 3-phosphoinositide-dependent protein kinase 1 and MAP kinase-a... | 1 | 5 |
| Protein kinase C theta type and Leucine-rich repeat serine/thr... | 1 | 1 |
| Transient receptor potential cation channel subfamily V member... | 4 | 0 |
| Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... | 5 | 3 |
| TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... | 2 | 2 |
| Casein kinase II subunit alpha and Homeodomain-interacting pro... | 5 | 0 |
| Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... | 5 | 0 |
| Somatostatin receptor type 3 and Potassium voltage-gated chann... | 3 | 0 |
| Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... | 2 | 2 |
| Transient receptor potential cation channel subfamily V member... | 4 | 0 |
| Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... | 6 | 12 |
| Transient receptor potential cation channel subfamily V member... | 6 | 2 |
| Methionine--tRNA ligase inhibitor N-[(4R)-6,8-dibromo-1,2,3,4-... | 1 | 1 |
| Growth hormone secretagogue receptor type 1 ligand SureCN36660... | 4 | 14 |
| Mitogen-activated protein kinase 14 inhibitor imidazole 81 family | 2 | 1 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152412 family | 8 | 0 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152398 family | 16 | 1 |
| Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... | 7 | 0 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 6 | 2 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 3 | 1 |
| Beta-secretase 1 and Potassium voltage-gated channel subfamily... | 3 | 4 |
| Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... | 17 | 0 |
| Somatostatin receptor type 3 and Potassium voltage-gated chann... | 3 | 3 |
| Somatostatin receptor type 3 and Somatostatin receptor type 4 ... | 5 | 1 |
| Serine/threonine-protein kinase PLK2 and Serine/threonine-prot... | 4 | 8 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206058 family | 5 | 0 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206614 family | 2 | 0 |
| Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... | 3 | 0 |
| Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... | 2 | 0 |
| Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... | 2 | 5 |
| C-C chemokine receptor type 2 and Potassium voltage-gated chan... | 2 | 2 |
| Tyrosine-protein kinase JAK1 and Aurora kinase A inhibitor CHE... | 2 | 0 |
| Protein kinase C theta type and Protein kinase C delta type in... | 9 | 0 |
| Translocator protein inhibitor CHEMBL2331870 family | 2 | 0 |
| CGMP-dependent protein kinase inhibitor SureCN14561191 family | 4 | 0 |
| Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... | 16 | 0 |
| TGF-beta receptor type-2 and Vascular endothelial growth facto... | 2 | 1 |
| Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... | 4 | 1 |
| ALK tyrosine kinase receptor ligand 3-[1-[(3-fluorophenyl)meth... | 2 | 0 |
| Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... | 9 | 2 |
| Calcitonin gene-related peptide type 1 receptor ligand N-[2-(7... | 16 | 0 |
| Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... | 2 | 8 |
| Eukaryotic translation initiation factor 2-alpha kinase 3 and ... | 4 | 0 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... | 1 | 1 |
| Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... | 2 | 3 |
| Cathepsin K inhibitor SureCN4141224 family | 3 | 0 |
| Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... | 5 | 13 |
| Cathepsin K and Cathepsin S inhibitor SureCN4138353 family | 3 | 0 |
| RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... | 16 | 7 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... | 3 | 0 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1-met... | 2 | 0 |
| LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-(3-cyanophenyl)-... | 4 | 0 |
| Mitogen-activated protein kinase 14 inhibitor 5-[2-(2,6-dichlo... | 1 | 0 |
| D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... | 1 | 0 |
| Epidermal growth factor receptor and Vascular endothelial grow... | 7 | 0 |
| Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... | 2 | 0 |
| Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... | 3 | 0 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 3 | 1 |
| 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... | 2 | 0 |
| 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... | 1 | 0 |
| 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... | 3 | 0 |
| Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... | 3 | 3 |
| Transient receptor potential cation channel subfamily V member... | 1 | 0 |
| Nociceptin receptor and Mu-type opioid receptor ligand SureCN5... | 1 | 0 |
| Serine/threonine-protein kinase B-raf inhibitor 1-[2-[[4-[2-cy... | 2 | 0 |
| Protein kinase C theta type and Protein kinase C delta type in... | 4 | 5 |
| Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... | 4 | 0 |
| G2/mitotic-specific cyclin-B2 and Cyclin-dependent kinase 1 in... | 2 | 1 |
| Gonadotropin-releasing hormone receptor ligand SureCN3275214 f... | 5 | 0 |
| Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... | 2 | 0 |
| Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... | 12 | 7 |
| Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... | 3 | 0 |
| Gonadotropin-releasing hormone receptor ligand 4-[[4-[2-(4-ter... | 3 | 3 |
| Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family | 2 | 0 |
| Kappa-type opioid receptor and Mu-type opioid receptor ligand ... | 2 | 0 |
| Serine/threonine-protein kinase B-raf inhibitor imidazole-base... | 2 | 0 |
| TGF-beta receptor type-1 and Mitogen-activated protein kinase ... | 1 | 0 |
| Nociceptin receptor and Mu-type opioid receptor ligand 2-(3-ch... | 2 | 0 |
| Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... | 4 | 0 |
| Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... | 9 | 0 |
| Gonadotropin-releasing hormone receptor ligand AGN-PC-00AWCA f... | 1 | 0 |
| Serine/threonine-protein kinase B-raf and Mitogen-activated pr... | 16 | 5 |
| 5-hydroxytryptamine receptor 3A ligand AGN-PC-077D8K family | 3 | 1 |
| cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... | 3 | 0 |
| Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... | 14 | 0 |
| Neuropeptide Y receptor type 5 ligand AGN-PC-01NS1A family | 7 | 0 |
| Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... | 2 | 0 |
| Dihydrofolate reductase type 1 and Dihydrofolate reductase inh... | 1 | 0 |
| Epidermal growth factor receptor and Receptor tyrosine-protein... | 1 | 0 |
Statistics of CFAM Database |
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
|
How to cite our database |
|
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
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Last update by |
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2014.08.29
|
