CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM501
Family Name 5-hydroxytryptamine receptor 2A and Potassium voltage-gated channel subfamily H member 2 ligand TEMANOGREL family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00312390 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and Prelamin-A/C Binder Superfamily
Class Class 3168

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Family 13 41
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 50 36
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 2
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 6 2
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 1 1
Poly [ADP-ribose] polymerase 1 inhibitor 1-(4-methoxyphenyl)-3... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-(3-me... 2 10
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 25 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-07R5ZB family 4 3
Cyclin-dependent kinase 2 inhibitor N-[(4-chlorophenyl)carbamo... 3 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00312393 CHEMBL1083725 Bioactive AGN-PC-07YIQF
CFAMM00312392 CHEMBL1082474 Bioactive AGN-PC-04TCA4
CFAMM00312391 CHEMBL1085155 Bioactive AGN-PC-00CNJH
CFAMM00312390 CHEMBL1084617 Bioactive TEMANOGREL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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