CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5014
Family Name Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ligand methyl 4-(3,4-difluorophenyl)-3-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-2,6-dimethyl-4H-pyrimidine-5-carboxylate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00360732 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Alpha-1D adrenergic receptor Binder Superfamily
Class Class 110

Cousin Family NamesSeedsMembers
Integrin alpha-4 Inhibitor R1295 Family 18 59
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Neuropeptide Y receptor type 1 Ligand BMS-193885 Family 3 11
Substance-K receptor Ligand MEN-14933 Family 13 154
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Neuropeptide Y receptor type 1 Ligand N-arylpiperazine Derivat... 5 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 13 2
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
C-X-C chemokine receptor type 3 ligand N-(2-ethoxyethyl)-N-[(1... 1 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Ghrelin/growth hormone secretagogue receptor and Cytochrome P4... 5 20
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 16 2
Histamine H3 receptor ligand AGN-PC-00AE5Q family 13 13
Histamine H3 receptor and Potassium voltage-gated channel subf... 28 30
Histamine H3 receptor ligand AGN-PC-03Z8HJ family 4 1
5-hydroxytryptamine receptor 7 ligand 4-[4-(2-ethoxyphenyl)pip... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00360732 CHEMBL145587 Bioactive methyl 4-(3,4-difluorophenyl)-3-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-2,6-dimethyl-4H-pyrimidine-5-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22060 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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