CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5029
Family Name Neuropeptide Y receptor type 1 ligand 2-[(4-chlorophenoxy)methyl]-4-(3-piperidin-1-ylpropoxy)-1-(3-piperidin-3-ylpropyl)benzimidazole family
No. of Seeds 5 No. of Other Members 13
Family Centroid CFAMM00360837 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 1 and Glutamate receptor ionotropic, NMDA 1 Binder Superfamily
Class Class 1268

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
B2 bradykinin receptor Ligand FR-173657 Family 44 180
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Tyrosine-protein kinase Lck inhibitor 4-N-(2-chloro-6-methylph... 8 45
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 10
Vascular endothelial growth factor receptor 2 and Fibroblast g... 10 3
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Neuropeptide Y receptor type 1 ligand 1-[3-[1-(cyclohexylmethy... 15 9
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 15
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 16 3
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 5 8
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Aromatase inhibitor 2-(imidazol-1-ylmethyl)-6-methoxy-1-phenyl... 2 8
Leukotriene A-4 hydrolase inhibitor AGN-PC-00EW8S family 1 2
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 1
D(2) dopamine receptor ligand SureCN11039666 family 1 4
5-hydroxytryptamine receptor 1A and Gonadotropin-releasing hor... 3 0
Metabotropic glutamate receptor 2 ligand 2-[[(1R,5S)-6-[(2,5-d... 2 3
5-hydroxytryptamine receptor 1A ligand AGN-PC-04UH85 family 2 3
Nociceptin receptor and Delta-type opioid receptor ligand 2-[3... 2 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Coagulation factor X inhibitor AGN-PC-07C2VY family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00360853 CHEMBL433734 Bioactive SureCN7688920
CFAMM00360837 CHEMBL61532 Bioactive 2-[(4-chlorophenoxy)methyl]-4-(3-piperidin-1-ylpropoxy)-1-(3-piperidin-3-ylpropyl)benzimidazole
CFAMM00360851 CHEMBL91462 Bioactive 2-[(4-chlorophenoxy)methyl]-4-(2-piperidin-4-ylethoxy)-1-(3-piperidin-3-ylpropyl)benzimidazole
CFAMM00360843 CHEMBL145714 Bioactive AGN-PC-075PQS
CFAMM00360842 CHEMBL330223 Bioactive 2-[(4-chlorophenoxy)methyl]-4-[3-[(3S)-piperidin-3-yl]propoxy]-1-[3-[(3S)-piperidin-3-yl]propyl]benzimidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27298 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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