CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5046
Family Name Coagulation factor X inhibitor benzothiophene compound, 4 family
No. of Seeds 9 No. of Other Members 10
Family Centroid CFAMM00360947 Functional Category Bioactive
Superfamily Atrial natriuretic peptide receptor 1 Ligand Ataciguat Superfamily
Class Class 1000

Cousin Family NamesSeedsMembers
Atrial natriuretic peptide receptor 1 Ligand Ataciguat Family 7 45
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 2 0
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-09M88E f... 1 7
Coagulation factor X inhibitor 3-chloro-N-[4-methyl-2-[(4-meth... 3 0
Thyroid hormone receptor beta and Cellular tumor antigen p53 l... 1 4
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Coagulation factor X inhibitor AGN-PC-04YPWA family 3 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Flap endonuclease 1 and DNA repair protein complementing XP-G ... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 2-chl... 1 7
Coagulation factor X and Prothrombin inhibitor SureCN6592460 f... 14 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
Coagulation factor X and Prothrombin inhibitor AGN-PC-046RBL f... 2 1
Coagulation factor X inhibitor AGN-PC-01V7DS family 3 0
Coagulation factor X and Prothrombin inhibitor SureCN6592952 f... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Coagulation factor X inhibitor benzothiophene compound, 16 family 1 0
Coagulation factor X inhibitor AGN-PC-078Y3R family 1 0


External ID

Functional Category

Molecule Name

CFAMM00360941 CHEMBL244461 Bioactive benzothiophene compound, 8
CFAMM00360949 CHEMBL150063 Bioactive 3-chloro-N-[2-[(4-chlorophenyl)carbamoyl]phenyl]-1-benzothiophene-2-carboxamide
CFAMM00360931 CHEMBL149756 Bioactive 3-chloro-N-[2-[(4-chlorophenyl)carbamoyl]-4-fluorophenyl]-1-benzothiophene-2-carboxamide
CFAMM00360947 CHEMBL149421 Bioactive benzothiophene compound, 4
CFAMM00360926 CHEMBL244247 Bioactive benzothiophene compound, 5
CFAMM00360946 CHEMBL356112 Bioactive 3-chloro-N-[4-chloro-2-[(4-chlorophenyl)carbamoyl]-6-methylphenyl]-1-benzothiophene-2-carboxamide
CFAMM00360935 CHEMBL145839 Bioactive 3-chloro-N-[4-chloro-2-[(4-chlorophenyl)carbamoyl]-5-fluorophenyl]-1-benzothiophene-2-carboxamide
CFAMM00360924 CHEMBL397661 Bioactive benzothiophene compound, 11
CFAMM00360942 CHEMBL146641 Bioactive 3-chloro-N-[2-[(4-chlorophenyl)carbamoyl]-5-methylphenyl]-1-benzothiophene-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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