CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM505
Family Name Vascular endothelial growth factor receptor 2 and Angiopoietin-1 receptor ligand AGN-PC-07ZFR8 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00169422 Functional Category Bioactive
Superfamily Cathepsin S and Collagenase 3 Binder Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
High affinity nerve growth factor receptor Ligand Lestaurtinib... 6 126
B-lymphocyte antigen CD20 Inhibitor Rituxan Immunology Family 10 17
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Serine/threonine-protein kinase mTOR inhibitor AGN-PC-093LHN f... 3 2
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 3 5
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 3
Rho-associated protein kinase 2 and Rho-associated protein kin... 2 6
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
Collagenase 3 and Matrix metalloproteinase-14 inhibitor 4-[[[5... 2 4
Angiopoietin-1 receptor and Vascular endothelial growth factor... 7 2
Vascular endothelial growth factor receptor 2 and Angiopoietin... 4 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 14 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 9 0
Tyrosine-protein kinase JAK3 inhibitor CHEMBL234066 family 1 2
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
High affinity nerve growth factor receptor ligand CHEMBL254555... 2 2
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 2 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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