CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A ligand CCT137690 family
No. of Seeds 10 No. of Other Members 23
Family Centroid CFAMM00312446 Functional Category Bioactive
Superfamily Aurora kinase A and GABA theta subunit Binder Superfamily
Class Class 1228

Cousin Family NamesSeedsMembers
Aurora kinase A and Potassium voltage-gated channel subfamily ... 8 7
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 11 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0


External ID

Functional Category

Molecule Name

CFAMM00312462 CHEMBL1651455 Bioactive SureCN13985733
CFAMM00312477 CHEMBL2203765 Bioactive 4-[4-[6-bromo-7-[4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl]-1H-imidazo[4,5-b]pyridin-2-yl]phenyl]morpholine
CFAMM00312447 CHEMBL1084636 Bioactive AGN-PC-07ZG5L
CFAMM00312476 CHEMBL2203766 Bioactive 1-[4-[4-[6-bromo-7-[4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl]-1H-imidazo[4,5-b]pyridin-2-yl]phenyl]piperazin-1-yl]ethanone
CFAMM00312464 CHEMBL1651457 Bioactive SureCN209196
CFAMM00312446 CHEMBL1236904 Bioactive CCT137690
CFAMM00312459 CHEMBL1084079 Bioactive AGN-PC-07ZZHH
CFAMM00312450 CHEMBL1085607 Bioactive 3-[[4-[6-bromo-2-[4-(piperazin-1-ylmethyl)phenyl]-1H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]methyl]-5-methyl-1,2-oxazole
CFAMM00312478 CHEMBL1086583 Bioactive AGN-PC-07ZG5V
CFAMM00312472 CHEMBL1082597 Bioactive SureCN13985590

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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