CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5105
Family Name Collagenase 3 and Stromelysin-1 inhibitor (2R,4S)-N-hydroxy-4-morpholin-4-yl-1-(4-pentylphenyl)sulfonylpyrrolidine-2-carboxamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00361380 Functional Category Bioactive
Superfamily Disintegrin and Collagenase 3 Binder Superfamily 4
Class Class 1114

Cousin Family NamesSeedsMembers
Thymidylate synthase Inhibitor N-[tosyl-d-prolinyl]amino-ethan... 1 10
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 10 1
Collagenase 3 and Macrophage metalloelastase inhibitor (2R)-N-... 1 2
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-(naphthalen-2... 3 1
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Growth hormone secretagogue receptor type 1 ligand [(3R)-3-ami... 2 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor 4-... 4 5
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 8 0


External ID

Functional Category

Molecule Name

CFAMM00361382 CHEMBL344778 Bioactive (2R,4S)-N-hydroxy-1-(4-pentylphenyl)sulfonyl-4-piperidin-1-ylpyrrolidine-2-carboxamide
CFAMM00361380 CHEMBL146256 Bioactive (2R,4S)-N-hydroxy-4-morpholin-4-yl-1-(4-pentylphenyl)sulfonylpyrrolidine-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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