CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5116
Family Name P2Y purinoceptor 1 inhibitor MRS-2279 family
No. of Seeds 11 No. of Other Members 45
Family Centroid CFAMM00361519 Functional Category Bioactive
Superfamily P2Y purinoceptor 1 Binder Superfamily
Class Class 4207

Cousin Family NamesSeedsMembers
Thyroid hormone receptor Ligand Dibrt Family 3 8
Adenosine receptor A3 and Adenosine receptor A1 ligand (1R,2R,... 10 15
Adenosine receptor A3 and Adenosine receptor A1 ligand (1S,2R,... 5 2


External ID

Functional Category

Molecule Name

CFAMM00361477 CHEMBL2373377 Bioactive [[(1S,5R)-4-[2-chloro-6-(methylamino)purin-9-yl]-2,3-dihydroxy-1-bicyclo[3.1.0]hexanyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
CFAMM00361490 CHEMBL2373948 Bioactive [(1S,2R,3S,4R,5R)-4-(6-amino-2-methylsulfanylpurin-9-yl)-2,3-dihydroxy-1-bicyclo[3.1.0]hexanyl]methyl phosphono hydrogen phosphate
CFAMM00361516 CHEMBL2112864 Bioactive [(1R,2S,4S,5S)-4-[2-chloro-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate
CFAMM00361509 CHEMBL603128 Bioactive [(1S,2R,3S,4R,5S)-4-(6-amino-2-chloropurin-9-yl)-2,3-dihydroxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate
CFAMM00361502 CHEMBL2373323 Bioactive [[(1S,5R)-4-(6-amino-2-chloropurin-9-yl)-2,3-dihydroxy-1-bicyclo[3.1.0]hexanyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
CFAMM00361515 CHEMBL2112867 Bioactive [(1R,2S,4S,5S)-4-[2-methyl-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate
CFAMM00361495 CHEMBL444278 Bioactive [(1R,2S,4S,5S)-4-[2-iodo-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate
CFAMM00361487 CHEMBL2373389 Bioactive [[(1S,5R)-4-(6-amino-2-methylsulfanylpurin-9-yl)-2,3-dihydroxy-1-bicyclo[3.1.0]hexanyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
CFAMM00361480 CHEMBL339873 Bioactive MRS-2279
CFAMM00361519 CHEMBL1628643 Bioactive MRS-2279
CFAMM00361485 CHEMBL146342 Bioactive [(1R,5S)-4-[2-bromo-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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