CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Neuronal acetylcholine receptor subunit alpha-7 and Neuronal acetylcholine receptor subunit alpha-4 ligand SureCN4109510 family
No. of Seeds 7 No. of Other Members 21
Family Centroid CFAMM00312544 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 5 and Neuronal acetylcholine receptor subunit alpha-4 Binder Superfamily
Class Class 3174

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
5-hydroxytryptamine receptor 2B Ligand Minaprine Family 2 42
Triple reuptake Inhibitor BMS-820836 Family 2 7
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 4 7
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 4 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 1
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 3-(2,... 3 9
Acetylcholinesterase inhibitor 1-[3-[6-[2-(1-benzylpiperidin-4... 1 0
Acetylcholinesterase inhibitor N-[2-(1-benzylpiperidin-4-yl)et... 1 0


External ID

Functional Category

Molecule Name

CFAMM00312533 CHEMBL168753 Bioactive N-(1-ethylpyrrolidin-2-yl)-6-phenyl-5-propylpyridazin-3-amine
CFAMM00312532 CHEMBL1628598 Bioactive 2-methyl-5-(6-phenylpyridazin-3-yl)-2-(tritritiomethyl)-5-aza-2-azoniabicyclo[2.2.1]heptane;iodide
CFAMM00312544 CHEMBL1082655 Bioactive SureCN4109510
CFAMM00312537 CHEMBL1082972 Bioactive (1R,4R)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane;iodide
CFAMM00312543 CHEMBL499074 Bioactive (3aS,6aR)-2-methyl-5-[6-(3-methylphenyl)pyridazin-3-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole;hydrochloride
CFAMM00312522 CHEMBL497943 Bioactive (3aS,6aR)-5,5-dimethyl-2-(6-phenylpyridazin-3-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-ium;iodide
CFAMM00312541 CHEMBL1083281 Bioactive SureCN1110460

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

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Professor in Department of Pharmacy
National University of Singapore, Singapore

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