CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5126
Family Name Cellular tumor antigen p53 and Thyrotropin receptor ligand CHEMBL1464055 family
No. of Seeds 1 No. of Other Members 19
Family Centroid CFAMM00361595 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily Cellular tumor antigen p53 and Thyrotropin receptor ligand CHEMBL1464055 Superfamily
Class Class 1777

Cousin Family NamesSeedsMembers
Ipriflavone family 62 2480
DNA topoisomerase 2-beta Inhibitor Howiinol A (ghm-10) Family 1 42
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Acetyl-CoA carboxylase 2 Inhibitor Soraphen A Family 2 80
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Beta-lactamase Inhibitor 4-carboxyphenylboronic Acid Family 1 1
Liver carboxylesterase 1 Inhibitor 2,2-dimethoxy-1,2-diphenyl-... 1 16
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor (5r,... 3 9
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
Squalene synthase Inhibitor Zaragozic Acid D2 Family 75 43
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Protein kinase C alpha type inhibitor [2-(hydroxymethyl)-5-oxo... 2 4
Protein kinase C delta type and Protein kinase C beta type inh... 3 9
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
Beta-lactamase inhibitor CHEMBL1358094 family 1 10
Hydroxycarboxylic acid receptor 2 and Hydroxycarboxylic acid r... 3 0
Microtubule-associated protein tau and Putative fructose-1,6-b... 1 1
Epoxides Metabolite Phenylmethylglycidic ester Family 2 17
Benzyloxycarbonyls Metabolite Benzyl acetoacetate Family 1 6
[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl] ben... 1 2
3-methyl-1-oxo-4H-isochromene-3-carboxylate NP Methyl 3-methyl... 4 1
3-(4-hydroxy-6-methyl-2-oxopyran-3-yl)-3H-2-benzofuran-1-one N... 2 2
methylbenzoate NP 7-oxocyclohepta-1,3,5-trien-1-yl 3-methylben... 2 1


External ID

Functional Category

Molecule Name

CFAMM00361584 CHEMBL2448607 Bioactive 2,3-bis[(4-methylbenzoyl)oxy]butanedioic acid;3-[(2R)-1-methylpyrrolidin-2-yl]pyridine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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