CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor 6 ligand AGN-PC-0BIUF2 family
No. of Seeds 25 No. of Other Members 11
Family Centroid CFAMM00312697 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine receptor 2B Binder Superfamily
Class Class 3175

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
Hepatocyte growth factor receptor Ligand SGX523 Family 1 15
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-03P3TZ family 6 88
5-hydroxytryptamine receptor 6 ligand AGN-PC-031XQS family 1 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
5-hydroxytryptamine receptor 6 ligand SureCN3399354 family 7 3
5-hydroxytryptamine receptor 6 ligand [3-(benzenesulfonyl)-5-m... 7 1
5-hydroxytryptamine receptor 6 ligand 3-(3-chloro-4-fluorophen... 1 2
5-hydroxytryptamine receptor 6 ligand 3-(benzenesulfonyl)-N,5-... 4 1
5-hydroxytryptamine receptor 6 ligand 3-(3-chlorophenyl)sulfon... 6 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07CBUP family 2 3
Glucose-dependent insulinotropic receptor ligand 4-({Ethyl-[1-... 6 12
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 2 3
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 3 1
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 3 5
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Casein kinase II subunit alpha inhibitor 7-(cyclopropylamino)-... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-0CSEAG family 2 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 2 0
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07R77D fa... 2 7
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C9 l... 2 5
Prostaglandin G/H synthase 2 and Cyclooxygenase 2 inhibitor Su... 2 6


External ID

Functional Category

Molecule Name

CFAMM00312710 CHEMBL1668591 Bioactive 3-(3-fluorophenyl)sulfonyl-N,5,7-trimethylpyrazolo[1,5-a]pyrimidin-2-amine
CFAMM00312716 CHEMBL1922626 Bioactive AGN-PC-0BIUIK
CFAMM00312702 CHEMBL1922630 Bioactive AGN-PC-07PWLF
CFAMM00312709 CHEMBL1922640 Bioactive AGN-PC-07PWOB
CFAMM00312715 CHEMBL1922625 Bioactive AGN-PC-0BIUIJ
CFAMM00312701 CHEMBL1922631 Bioactive AGN-PC-0BIUMA
CFAMM00312708 CHEMBL2172187 Bioactive CHEMBL2172187
CFAMM00312714 CHEMBL1922624 Bioactive AGN-PC-0BIUII
CFAMM00312718 CHEMBL1922629 Bioactive AGN-PC-0BFI85
CFAMM00312700 CHEMBL1922614 Bioactive AGN-PC-0BFI84
CFAMM00312698 CHEMBL1922618 Bioactive AGN-PC-0BIUF1
CFAMM00312713 CHEMBL1083076 Bioactive AGN-PC-071SNE
CFAMM00312691 CHEMBL2172193 Bioactive CHEMBL2172193
CFAMM00312717 CHEMBL1922627 Bioactive AGN-PC-0BIUIM
CFAMM00312699 CHEMBL1922633 Bioactive AGN-PC-07PWLI
CFAMM00312697 CHEMBL1922619 Bioactive AGN-PC-0BIUF2
CFAMM00312705 CHEMBL1922634 Bioactive AGN-PC-07PWMV
CFAMM00312690 CHEMBL1082762 Bioactive AGN-PC-07ZZRR
CFAMM00312696 CHEMBL1922639 Bioactive AGN-PC-07PWMO
CFAMM00312704 CHEMBL1922636 Bioactive AGN-PC-07PWO4
CFAMM00312711 CHEMBL1668592 Bioactive 3-(4-fluorophenyl)sulfonyl-N,5,7-trimethylpyrazolo[1,5-a]pyrimidin-2-amine
CFAMM00312695 CHEMBL1668584 Bioactive SureCN8042438
CFAMM00312721 CHEMBL1922632 Bioactive AGN-PC-0BFI9U
CFAMM00312703 CHEMBL1922637 Bioactive AGN-PC-0BIUMB

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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