CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor 6 ligand N-[[(1R)-6-(benzenesulfonyl)-8-fluoro-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]acetamide family
No. of Seeds 8 No. of Other Members 2
Family Centroid CFAMM00312725 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and Cytochrome P450 2D6 Binder Superfamily
Class Class 2173

Cousin Family NamesSeedsMembers
SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand T... 3 35
Alpha-2A adrenergic receptor Ligand SK&F-29661 Family 3 42
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-acet... 6 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-valp... 8 5
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
5-hydroxytryptamine receptor 6 ligand [(1R)-6-(3-fluorophenyl)... 6 6
5-hydroxytryptamine receptor 6 ligand (1R)-1-[(dimethylsulfamo... 10 4
5-hydroxytryptamine receptor 6 ligand N-[[(1R)-6-(3-fluorophen... 8 0
5-hydroxytryptamine receptor 6 ligand 2-[[(1R)-6-(3-fluorophen... 4 0
5-hydroxytryptamine receptor 6 and Cytochrome P450 2D6 ligand ... 2 0
Cathepsin K inhibitor (1R,2R)-N-(cyanomethyl)-5,5-difluoro-2-[... 6 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 1


External ID

Functional Category

Molecule Name

CFAMM00312728 CHEMBL1085120 Bioactive N-[[(1R)-6-(3-fluorophenyl)sulfonyl-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-2-hydroxyacetamide
CFAMM00312727 CHEMBL1084875 Bioactive N-[[(1R)-6-(3-fluorophenyl)sulfonyl-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-N-methylacetamide
CFAMM00312733 CHEMBL1083780 Bioactive N-[[(1R)-6-(3-fluorophenyl)sulfonyl-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-2-hydroxy-2-methylpropanamide
CFAMM00312726 CHEMBL1083886 Bioactive N-[[(1R)-6-(3-fluorophenyl)sulfonyl-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]acetamide
CFAMM00312732 CHEMBL1084358 Bioactive N-[[(1R)-6-(3-fluorophenyl)sulfonyl-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-2-methoxyacetamide
CFAMM00312725 CHEMBL1082777 Bioactive N-[[(1R)-6-(benzenesulfonyl)-8-fluoro-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]acetamide
CFAMM00312731 CHEMBL1084359 Bioactive N-[[(1R)-6-(3-fluorophenyl)sulfonyl-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-2,2-dimethylpropanamide
CFAMM00312730 CHEMBL1084604 Bioactive N-[[(1R)-8-fluoro-6-(3-fluorophenyl)sulfonyl-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-2-hydroxyacetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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