CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5182
Family Name Coagulation factor X inhibitor AGN-PC-00FGDC family
No. of Seeds 11 No. of Other Members 5
Family Centroid CFAMM00361896 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Binder Superfamily 9
Class Class 3238

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor Apixaban Family 34 52
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Coagulation factor X and Trypsin-1 inhibitor SureCN3836037 family 5 4
Coagulation factor X and Prothrombin inhibitor 2-(3-amino-1,2-... 5 3
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 15 2
Coagulation factor X inhibitor 1-(4-methoxyphenyl)-7-oxo-6-[4-... 5 0
Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphe... 8 0
Coagulation factor X inhibitor AGN-PC-046QD2 family 6 0
Coagulation factor X inhibitor SureCN6785555 family 7 0
Coagulation factor X inhibitor 2-(4-methoxyphenyl)-N-[5-(2-sul... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Coagulation factor X inhibitor AGN-PC-046RMQ family 1 0
Coagulation factor X inhibitor 2-[4-[2-[[(3S)-3-hydroxypyrroli... 1 0
Coagulation factor X inhibitor AGN-PC-077MYE family 16 0
Coagulation factor X inhibitor SureCN5644036 family 30 0
Coagulation factor X inhibitor AGN-PC-077MVW family 5 0
Coagulation factor X inhibitor SureCN5644554 family 2 0
Progesterone receptor ligand AGN-PC-00OK6E family 1 0


External ID

Functional Category

Molecule Name

CFAMM00361896 CHEMBL149260 Bioactive AGN-PC-00FGDC
CFAMM00361895 CHEMBL149583 Bioactive 2-(4-methoxyphenyl)-N-[4-(2-sulfamoylphenyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00361894 CHEMBL146793 Bioactive N-arylpyrazole carboxamide 3
CFAMM00361908 CHEMBL345731 Bioactive 2-[2-(aminomethyl)-4-methoxyphenyl]-5-methyl-N-[4-(2-sulfamoylphenyl)phenyl]pyrazole-3-carboxamide
CFAMM00361901 CHEMBL151627 Bioactive AGN-PC-009WVK
CFAMM00361907 CHEMBL151201 Bioactive AGN-PC-004RY2
CFAMM00361893 CHEMBL252650 Bioactive 2-[3-fluoro-4-[2-[2-(4-methoxyphenyl)-5-(trifluoromethyl)pyrazol-3-yl]-2-oxoethyl]phenyl]benzenesulfonamide
CFAMM00361900 CHEMBL147132 Bioactive AGN-PC-004R2C
CFAMM00361906 CHEMBL151750 Bioactive 2-[2-(aminomethyl)-4-methoxyphenyl]-N-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00361898 CHEMBL148718 Bioactive AGN-PC-006GMP
CFAMM00361897 CHEMBL212974 Bioactive AGN-PC-03K45K

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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