CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5188
Family Name Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ligand AGN-PC-0761SD family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00179064 Functional Category Bioactive
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 4
Class Class 2162

Cousin Family NamesSeedsMembers
Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 13 18
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 7 5
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Oxysterols receptor LXR-alpha Ligand N-{4-[2-(4-methoxyphenyl)... 3 16
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Survival motor neuron protein inhibitor CHEMBL1303282 family 1 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 1
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 3 8
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Microsomal triglyceride transfer protein large subunit inhibit... 3 0
Cathepsin K inhibitor (1R,2R)-N-(cyanomethyl)-2-[4-(3-methoxyp... 2 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 8
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 1 2
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
5-hydroxytryptamine receptor 1A ligand 3-hydroxy-6-iodo-2-[2-[... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 10
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 2
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 0
Cannabinoid receptor 2 ligand N-[(Z)-(6-methoxy-2-oxo-1-pentyl... 2 13
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor (4aS... 10 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 0
Melanin-concentrating hormone receptor 1 ligand N-[3-[1-[3-[4-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00361938 CHEMBL207069 Bioactive AGN-PC-00AL85

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24317 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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