CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5217
Family Name D(4) dopamine receptor and D(3) dopamine receptor ligand SureCN6906052 family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00181934 Functional Category Bioactive
Superfamily Beta-lactamase and DNA polymerase beta Binder Superfamily 5
Class Class 1183

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3 27
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 3 67
Beta-2 adrenergic receptor Ligand Olodaterol Family 16 27
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Renin Inhibitor Ro-66-1168 Family 10 30
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Poly [ADP-ribose] polymerase 1 inhibitor 6-[1-(2,3-dihydro-1,4... 1 30
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3... 2 3
Renin inhibitor 6-[[(2R)-1-[4-[3-[(2-methoxyphenyl)methoxy]pro... 3 1
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 8 0
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-01ZLS4 family 2 8
Transient receptor potential cation channel subfamily V member... 3 15
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 9
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 11 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Neuropeptide Y receptor type 5 ligand 2-(7-chloro-3-oxo-1,4-be... 3 3
Transient receptor potential cation channel subfamily V member... 1 0
Renin and Cytochrome P450 3A4 inhibitor SureCN6719989 family 2 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
5-hydroxytryptamine receptor 7 ligand 1-(2-methoxyphenyl)-4-[2... 6 2
Poly [ADP-ribose] polymerase 1 inhibitor 6-[[4-(4-chlorophenyl... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand (5R)-... 2 0
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 2 1
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 10 2
Progesterone receptor ligand CHEMBL252850 family 2 0
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-0034EG family 5 2
C-C chemokine receptor type 5 ligand dimethyl-[[4-[[7-(4-methy... 7 8
5-hydroxytryptamine receptor 1A ligand (1R,2R)-2-[4-(2,3-dihyd... 2 3
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 10
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1
Melanin-concentrating hormone receptor 1 and D(2) dopamine rec... 1 0
D(3) dopamine receptor ligand rac S 33138 family 1 0
Transient receptor potential cation channel subfamily V member... 1 2
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 5 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 12
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 9 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Mineralocorticoid receptor and Glucocorticoid receptor ligand ... 2 0
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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