CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5225
Family Name Delta-type opioid receptor and Mu-type opioid receptor ligand (Z)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-(2-methoxyphenyl)-N-prop-2-enylpropanamide family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00362330 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and D(2) dopamine receptor Binder Superfamily
Class Class 217

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
D(4) dopamine receptor ligand AGN-PC-004XJQ family 2 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 10
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 3 1
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3... 2 1
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 0


External ID

Functional Category

Molecule Name

CFAMM00362333 CHEMBL1744191 Bioactive (E)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-ethyl-N-(2-methoxyphenyl)-2-methylpropanamide
CFAMM00362332 CHEMBL1794881 Bioactive (E)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-(2-methoxyphenyl)-N-propylpropanamide
CFAMM00362331 CHEMBL1744167 Bioactive (Z)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-(2-methoxyphenyl)-N-prop-2-ynylpropanamide
CFAMM00362330 CHEMBL1744168 Bioactive (Z)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-(2-methoxyphenyl)-N-prop-2-enylpropanamide
CFAMM00362336 CHEMBL1744186 Bioactive (E)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-(2-ethoxyphenyl)-N-methylpropanamide
CFAMM00362329 CHEMBL1744169 Bioactive (Z)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-(2-ethoxyphenyl)-N-propylpropanamide
CFAMM00362335 CHEMBL1744187 Bioactive (Z)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-(2-methoxyphenyl)-N-methylpropanamide
CFAMM00362328 CHEMBL1744170 Bioactive (E)-but-2-enedioic acid;2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-ethyl-N-(2-methoxyphenyl)propanamide
CFAMM00362334 CHEMBL147150 Bioactive AGN-PC-00KOV4

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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