CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5227
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand tert-butyl 5-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate family
No. of Seeds 15 No. of Other Members 28
Family Centroid CFAMM00362371 Functional Category Bioactive
Superfamily GABA theta subunit and Gamma-aminobutyric acid receptor subunit pi Binder Superfamily 5
Class Class 1259

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand Zopiclone Family 2 1
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Flumaz... 10 100
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 24 0
Gamma-aminobutyric acid receptor subunit alpha-5 and Gamma-ami... 1 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 9 5


External ID

Functional Category

Molecule Name

CFAMM00362358 CHEMBL166267 Bioactive SureCN9078327
CFAMM00362381 CHEMBL166357 Bioactive SureCN9078086
CFAMM00362392 CHEMBL279165 Bioactive tert-butyl 5-[(3R,5S)-3,5-dimethylpiperazine-1-carbonyl]-7-methyl-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00362351 CHEMBL263211 Bioactive tert-butyl 7-fluoro-5-[(3S,5R)-3,4,5-trimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00362376 CHEMBL274685 Bioactive tert-butyl 7-methyl-5-[(3R)-3-methylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00362359 CHEMBL555381 Bioactive AGN-PC-07BY87
CFAMM00362365 CHEMBL416897 Bioactive SureCN9078308
CFAMM00362356 CHEMBL15079 Bioactive SureCN9077632
CFAMM00362374 CHEMBL14716 Bioactive tert-butyl 5-[(3S,5R)-3,5-dimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00362384 CHEMBL15102 Bioactive tert-butyl 5-[(3S,5R)-3,5-dimethylpiperazine-1-carbonyl]-7-fluoro-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00362388 CHEMBL14983 Bioactive SureCN9076155
CFAMM00362383 CHEMBL15276 Bioactive AGN-PC-0746XY
CFAMM00362371 CHEMBL14847 Bioactive tert-butyl 5-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00362382 CHEMBL277558 Bioactive tert-butyl 7-methyl-5-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00362377 CHEMBL277136 Bioactive tert-butyl 5-[(3R,5R)-3,5-dimethylpiperazine-1-carbonyl]-7-methyl-4H-imidazo[1,5-a]quinoxaline-3-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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