CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5255
Family Name Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-01ZFI4 family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00362662 Functional Category Bioactive
Superfamily Endothelin-1 receptor and Endothelin B receptor Binder Superfamily 10
Class Class 3152

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 3 101
Endothelin-1 receptor Ligand BMS-182874 Family 6 10
Prostaglandin E2 receptor EP3 subtype ligand AGN-PC-07Z9FK family 2 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 13 23
Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-... 1 0
Endothelin-1 receptor and Endothelin B receptor ligand N-[[2-[... 1 0
Endothelin-1 receptor and Type-1 angiotensin II receptor ligan... 6 1
Type-1 angiotensin II receptor and Endothelin-1 receptor ligan... 1 1
Endothelin-1 receptor and Endothelin B receptor ligand SureCN7... 1 1
5-hydroxytryptamine receptor 6 ligand 3,5-dimethyl-N-[3-[[(2R)... 1 0


External ID

Functional Category

Molecule Name

CFAMM00362662 CHEMBL149232 Bioactive AGN-PC-01ZFI4
CFAMM00362660 CHEMBL148719 Bioactive AGN-PC-03KEOT
CFAMM00362659 CHEMBL345951 Bioactive SureCN7951160
CFAMM00362665 CHEMBL147340 Bioactive AGN-PC-01ZFI3

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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